DOI: 10.1056/NEJMoa1800389 Guasch-Ferre, M., Pacheco, L.S., Tessier, A.J., et al
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Out of the differentially expressed genes, 1140 were upregulated, while the remaining 1219 were downregulated
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First-time users or those with sensitive constitutions are recommended to start at 50 mg daily for 12 weeks to observe body tolerance