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Dubravicky, V

The treatment of type 2 diabetes requires positive modulation of GLP-1R to inhibit glucagon secretion and stimulate insulin secretion in a glucose-dependent manner 2

Under compression, hydrostatic pressure is created within the gelatinous NP, which in turn generates tensile stress (or hoop stress) in the surrounding cartilaginous layers of the AF to counteract the original load [6]