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Patients should be aware that if they experience concerning symptoms whilst taking B12 supplements, they should discuss this with their GP and report suspected adverse reactions via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)

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Two homologous NRP isoforms are known to exist, namely NRP1 and NRP2, encoded by distinct neuropilin genes ( Nrp1 and Nrp2 ) 315,316,317

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