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PS-MPs activate both protective (Nrf2-Keap1) and apoptotic (p53Bcl-2/Bax) pathways

Thus, elevated carnitine metabolites may reflect a neuroprotective response to compensate for metabolic dysfunction, resulting in RGC death

[DOI] [PMC free article] [PubMed] [Google Scholar] 250.Szwajgier D., Borowiec K., Pustelniak K

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(2021) recently uncovered a larger rigid core for purified PrP fibrils from hamster brains, composed of residues 95227, with a structural arrangement that differs from structural models of non-infectious fibrils