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Taken together, this work reinforces guidance to ensure adequate micronutrient intake before and during pregnancy and suggests that standard supplements may help lower autism risk
Possible concerns encompass herbdrug interactions (e.g., botanical substances influencing cytochrome P450 enzymes), ocular surface toxicity resulting from extended use of certain extracts or preservatives in formulations, and systemic adverse effects from oral supplementation
Medications that can induce B6 deficiency or antagonize its actionsuch as isoniazid, cycloserine, hydralazine, and penicillaminemay necessitate supplemental B6 under medical supervision
For laboratory preparation, up to 5 mL of bacteriostatic water or another suitable research solvent may be added to reconstitute the blend into a clear multi-dose solution