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5-Amino-1MQ blocks the activity of NNMT and reduces the levels of its product, methylnicotinamide (MNA)

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227 In another randomized placebo-controlled trial, patients with high cholesterol took 80 mg of atorvastatin (Lipitor) (a common lipid-lowering medication that blocks cholesterol production) for four weeks and then added either 180 mg of bempedoic acid or placebo to their treatment regimen for four additional weeks