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A primary drawback of subcritical water extraction is the requirement for high temperatures, typically between 100C and 374C, which can cause thermal degradation of heat-sensitive polyphenolic compounds, thereby reducing their yield and bioactivity ( Moreover, at elevated temperatures, subcritical water extraction tends to be less selective, extracting a wider range of plant matrix components, which can complicate downstream purification ( Subcritical water extraction equipment requires more rigorous maintenance and corrosion prevention due to the high reactivity and corrosiveness of water at elevated temperature and pressure ( 3.1.6 Pulsed electric field method A nonthermal method that employs high-voltage pulses between two electrodes arranged in a sandwich configuration

J Small Anim Pract 65(3):153175 Pei J, Pan X, Wei G, Hua Y (2023) Research progress of glutathione peroxidase family (GPX) in redoxidation

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Follow-up dose: 2 vials (600 mg each) every 12 hours