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Brain histone beta-hydroxybutyrylation couples metabolism with gene expression

We speculate that the resemblance between MOG mutants and mated hermaphrodites stems from two unique combinations in the MOG mutants: (i) Their masculinized germline produces a large number of sperm, high levels of male-specific metabolites 56 , and likely other male-derived seminal fluid components

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Semaglutide GLP-1 works by affecting the hypothalamus area of the brain, which is the region tasked with controlling hunger and fullness cues