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The injection should be given in the middle third of both axes

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Continuous use without breaks may reduce its long-term effectiveness and increase adaptation

(Dali-Youcef and Andrs, 2009) Other people at risk include those who have had intestinal surgeries, or have chronic conditions which affect the gut , such as Crohns disease or celiac disease (Dahele and Ghosh, 2001)

The choice between these approaches depends on individual goals and priorities