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Need for Large-Scale, Prospective Studies To address these gaps, large-scale, prospective, randomized controlled trials are needed to: Evaluate the analgesic efficacy of paracetamol as monotherapy and as part of combination regimens with opioids and adjuvant analgesics in various cancer populations

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The sections were mounted on 3-aminopropyltriethoxysilane (Sigma-Aldrich, Buenos Aires, Argentina)-coated slides and a subsequent microwave pretreatment for antigen retrieval was performed

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