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For these cases, Al-Aly wondered if what he was hearing from his patients about how they were able to quit drinking or smoking after starting GLP-1 medication might apply more broadly to any substance

According to Reuters, the weight loss data compares favourably with semaglutide (sold as Ozempic), with trials for that injectable treatment showing patients living with diabetes lost around 6% of their body weight on the highest dose

doi: 10.1016/j.rvsc.2019.05.016

A 2025 study found that people taking GLP-1 medications performed significantly worse on taste tests across all five basic tastes, sweet, salty, sour, bitter and umami, while their sense of smell remained largely unchanged