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This was surprising considering the theoretical isoelectric point based on the amino acid sequence of the capsid structural proteins is 6.1 (Tummanapelli and Vasudevan, 2015)

KPV has demonstrated ability to accelerate mucosal healing and alleviate inflammation in colitis models

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Given the relatively high frequency of this enzyme deficiency in several regions of the world, this finding might be of practical importance to tailor surveillance guidelines and facilitate risk stratification