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This variation in treatment effect is suspected to be due to differences in medications, differences in methodology for lean mass assessment, and different lifestyle interventions prescribed in combination with pharmacological therapies [71]

Indeed, only 2 months later (September 2023), Intuitive was already fielding worst case scenarios conference questions: People are sitting there worried, well, bariatric is going to slow, I don't know how much because of GLP-1s

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NICE guidance (NG28) recommends assessing treatment response after 6 months, with continuation criteria based on HbA1c reduction and weight loss thresholds for GLP-1 receptor agonists