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During the first 2 to 4 weeks, you may experience: Nausea : Often most pronounced after meals, typically improving over time Reduced appetite : You may feel full more quickly and have less interest in food Mild abdominal discomfort : Bloating or a feeling of fullness Altered bowel habits : Either constipation or loose stools Fatigue : Some patients report tiredness as their body adjusts These effects are generally mild to moderate and tend to diminish as your body adapts to the medication

Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters

This is due to high costs associated with bringing new small molecule and protein drugs to market 38

The goal is not the highest possible dose, but the dose that works best for your body and lifestyle

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