The major types of gastrointestinal (GI) cancers include colorectal cancer, gastric cancer, esophageal cancer, liver cancer, and pancreatic cancer, each with distinct risk factors, clinical presentations, and treatment challenges
Collagen Collagen is the most abundant protein in the body and is responsible for maintaining the integrity of the skin, joints, and bones
SAG uses a thioester (S-acyl) bond, which is cleaved specifically by cytoplasmic thioesterases, offering a more targeted intracellular release mechanism with a cleaner safety profile demonstrated in human dosing studies
PMID: 137 StreetMCirilloFCatellaniCDaurizMLazzeroniPSartoriCet al
Other irAE research has focused on the role of human leucocyte antigen (HLA) genes, a complex of genes involved in regulating immune responses, that may be implicated in the development of particular autoimmune diseases, such as atopic dermatitis and IBD