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Below, we share the skinny on this game-changer for medical weight loss and answer FAQs about semaglutide weight loss injections

The medication was well tolerated and adverse effects were similar between treatment arms

On April 1, 2026, the FDA reiterated its enforcement policy: it does not currently intend to take action where a 503A compounder fills four or fewer prescriptions per calendar month of a drug that is "essentially a copy." That safe harbor is narrow, and it signals the FDA's direction

The same 28-day room temperature rule applies

More serious but less common side effects to watch for at this dose include acute pancreatitis (symptoms: severe abdominal pain radiating to the back, nausea, vomiting), gallbladder problems (symptoms: sudden pain in the upper right abdomen, fever, jaundice), and significant hypoglycemia if combined with certain diabetes medications