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UAE Research into Melanotan 1 has focused on its role in stimulating melanin production by binding to melanocortin receptors in skin cells
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doi:10.1186/s12876-019-1055-4
A 2024 review from the University of Illinois Chicago Drug Information Group, which summarizes recommendations from multiple clinical guidelines, notes that many experts recommend continuing naltrexone for at least 3 to 6 months, with longer treatment individualized based on a persons response and goals