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Taken together, these data confirm that the activity of UCK2 to restore UMP levels is the driving force behind increased PGC1mTOR-linked mitochondrial biogenesis to resolve pyrimidine stress when cells are treated with 5FU

Perlmutter is a frequent lecturer at Columbia University, Scripps Institute, New York University, and Harvard University and serves as an Associate Professor at the University of Miami Miller School of Medicine

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Effects of intensive control of glycemia on clinical kidney outcomes in type 2 diabetes patients compared with standard control: a meta-analysis

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