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These results demonstrated that administering hepsin afforded protection against APAP-induced liver damage in adult wild-type mice and ultimately prolonged their survival

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Reimer RJ, Chaudhry FA, Gray AT, Edwards RH

While clinical development for obesity was discontinued in 2007 after a Phase IIb trial failed to achieve its primary endpoint, the peptide remains a valuable research tool for investigating adipose tissue biology, lipolytic pathways, and receptor-independent signaling mechanisms

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