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Apoptosis describes a programmed mode of cell death that is characterized by a series of biochemical events that ultimately lead to cell fragmentation into compact membrane-enclosed structures, called apoptotic bodies that are taken up by neighboring cells and phagocytes, preventing inflammation, and tissue damage (Taylor et al., 2008)

More importantly, we focus on multiple respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), fibrosis, bronchiectasis, and pneumonia

Merck Manual: Professional Version

This conclusion was further confirmed by using hemin, an agonist of HO-1 enzymatic activity (Supplementary Fig