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As ionization efficiency between malonylated and propionylated peptides are different, the peak areas of malonylated peptides were converted into those of propionylated peptides using authentic peptides as previously described 20 (Table S3), except for the peptide containing H3K27, K36, and K37, where the ionization correction could not be conducted because there are three lysine residues on the peptide

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About 1/3 of RA patients are ACPA or RF negative, which makes early diagnosis of RA challenging

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Guidelines & Protocols Advisory Committee