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Tirzepatide produced greater average weight reduction in the direct SURMOUNT-5 obesity trial, with mean weight loss of 20.2% compared with 13.7% for semaglutide at 72 weeks

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The free mitochondria may act as signals in cell-to-cell communication

Relaying of this signal to other parts of the body, such as the liver, pancreas or brain is then required in turn to engage appropriate responses, such as getting the body ready to digest the food, prepare insulin release and to make us feel full