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Referral Process: see referral guidelines section M.A , S.S & A.C 09-04-26 Who to refer: Refer the following patients to the Lets Prevent Diabetes Programme: Pre-diabetes : Refer patients withPre-diabetes (HbA1C 42 47, impaired fasting glucose, impaired glucose tolerance), or patients who are at high risk of developing diabetes for other reasons (see primary care management tab for risk stratification)

The authors concluded: The use of GLP-1 agonists should be considered in T1DM patients who are overweight or obese and not at glycemic goals despite aggressive insulin therapy. After conducting clinical trials with a GLP-1 agonist, Novo Nordisk decided not to pursue FDA approval for treating type 1 diabetes

Whilst Ozempic has gained attention for its weight loss effects, it is important to note that in the UK, it is specifically licensed for diabetes management and cardiovascular risk reduction in patients with type 2 diabetes and established cardiovascular disease

Consistent with the impact of estrous phase on the weight loss response, semaglutide-induced behavioral disruption was also estrous phase-dependent, being greatest during proestrus (Fig