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cerevisae , which can run transsulfuration in either direction, has two sets of transsulfuration enzymes one for the Hcy Cys direction and one for the Cys Hcy direction thereby further emphasizing the dedicated directionality of the enzymes on the pathway [121, 136]

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The model is most useful for understanding accumulation patterns, steady state timing, and comparing dosing approaches rather than predicting exact personal blood levels