fda glp-1 compounding enforcement november 2025 regulators, customs officers, and physicians around the world are continuing to raise alarms about unsafe and unregulated weight-loss and peptide products. An FDA warning letter to ProRx states the company continued Fight over GLP-1 compounding plays

Market outlook: Global sales projected to exceed $100B by 2030

The peptide bypasses the UV damage requirement entirely by directly stimulating melanocyte activity through the cAMP-PKA signaling pathway, meaning pigmentation develops in skin areas that never see sunlight

BMO Capital Markets analysts expect a slow launch, however, writing in a note to investors about challenges including a black box warning for risk of acute adrenal insufficiency or adrenal crisis with inadequate concomitant glucocorticoid therapy. The firm said it anticipates broad commercial access will not happen until the second half of 2025

These differences may reflect species-specific factors, including drug administration routes, dosing and diets as well as differences in tolerance or drug clearance rates, said de Jonghe

Glossary Telogen effluvium: a temporary, usually reversible form of diffuse hair shedding, often triggered a few months after weight loss, illness or stress