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Within the toxicological community, it is generally accepted that, whereas the widely used analgesic and antipyretic drug acetaminophen ( N -acetyl- para -aminophenol) causes dose-dependent liver toxicity in humans and in various animal species, its regioisomer N -acetyl- meta -aminophenol (AMAP) does not

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qPCR was performed using a 2 Universal Blue SYBR Green qPCR Master Mix (Servicebio) on a real-time PCR system (Applied Biosystems)