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The active form of B6, pyridoxal 5-phosphate (PLP), is required by the enzyme aromatic L-amino acid decarboxylase (AADC), which catalyzes the final step in producing both serotonin from tryptophan and dopamine from L-DOPA
The cardiovascular safety and efficacy of tirzepatide in adults with T2D has been assessed in a large phase 3 clinical trial (SURPASS-CVOT) (Table 1) [88]
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According to PubMed Central studies show patients may lose 15 percent or more of their starting body weight over several months
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