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These findings point to an optimal physiological range in which C-peptide appears to support metabolic stability, while both deficiency and excess may be associated with adverse outcomes

[PubMed] [PMC] Verkhratsky A, Butt A, Li B, Illes P, Zorec R, Semyanov A, Tang Y, Sofroniew MV (2023) Astrocytes in human central nervous system diseases: a frontier for new therapies

Thus, even if amyloids help protect us from pathogens, as we age, mitochondrial dysfunction can eventually turn the genes that express these amyloids against us