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NLRP3 Inflammasomea key player in antiviral responses

More structural information is needed to fully understand how AIM recognises DAMPs and other targets as well as its association with AIM binding partners that work as effectors

Our lead compound, Auxora, has the potential to address broad unmet need in critical care by improving outcomes in life-threatening conditions for which there are no-approved disease-modifying treatments

For RNA extraction, TRIzol reagent (Thermo Fisher Scientific, Waltham, MA, USA) was used to isolate total RNA from both cells

In addition, for the first year of the model, we will notify preliminarily eligible clinicians of their expected selection for the model to provide additional time to prepare and anticipate operational updates