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Primary brain microvascular endothelial cells (BMECs) were isolated and preincubated with different concentrations of insulin or ITP, after which the uptake of FITC-labeled ITP or FITC-labeled insulin by the BMECs was measured by flow cytometry (Supplementary Fig

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Samples were further processed according to a protocol modified from ref

In September 2025, researchers at UCLA published a study in ACR Open Rheumatology (Kellner and colleagues)