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Rajeswaran FRCP(UK);MSc Consultant Physician Obesity, Diabetes & Endocrinology

Considering duplicate or implausible reports can lead to significant errors [22], extensive cleaning, and normalization were conducted to ensure interpretable data (detailed process is provided in Additional file 1: Fig S1[23,24,25])

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This finding is clinically significant: the individuals who respond most strongly to afamelanotide are the same individuals whose baseline pigmentation provides the least UV protection