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Zhang J, Quan C, Wang C, Wu H, Li ZM, Ye Q (2016) Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production

Unlike many single-target agents, SFNs ability to simultaneously engage multiple vulnerability nodes in cancer cells reduces the likelihood of resistance development and enhances its therapeutic potential

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Based on these findings, we propose an intrinsic agonist model of the ECD for GLP-1R activation, in which the ECD is the major determining factor in activation of GLP-1R (Figure 9)