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Semaglutide is a GLP-1 receptor agonist that enhances insulin secretion, slows gastric emptying, and suppresses appetite through the GLP-1 receptor

Inui, M., Martello, G

Cycling protocols 8 weeks on, 4 weeks off are standard practice in part because the effects of chronic continuous use are simply unknown

DPP-4 inhibitors are generally discontinued when starting GLP-1 medications since both affect the incretin system

Optimal gut health also influences how the body stores and utilises fat, promoting its breakdown and preventing excessive accumulation. By maintaining a diet rich in fibre, fermented foods and prebiotics, individuals can support their gut health and improve their weight management efforts