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This increase in energy expenditure can contribute to a more significant reduction in weight when combined with the effects of GLP-1 and GIP

Gagn-Ouellet V, Houde AA, Guay SP, Perron P, Gaudet D, Gurin R, Jean-Patrice B, Hivert MF, Brisson D, Bouchard L

Antagonism of central glucagon-like peptide-1 receptors enhances lipopolysaccharide-induced fever 85(1-3), 101

Before starting NAD+ therapy, here are a few important considerations: Avoid use during pregnancy or breastfeeding

Notably, discontinuation is associated with weight regain and partial or complete reversal of improvements in cardiometabolic risk factors, including inflammatory markers, blood pressure, lipid profile, and blood glucose levels