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They enable a deeper understanding of the interplay between immune responses, neuroinflammation, and genetic modifications, paving the way for targeted and innovative therapeutic strategies

ORCID: Affiliation: 11 Department of Neuroscience and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, 20149 Milano, Italy 12 Department of Pathophysiology and Transplantation, Dino Ferrari Center, Universit degli Studi di Milano, 20122 Milano, Italy These authors contributed equally to this work

Once both substrates are bound at the enzyme's active site, the monomeric GST interacts with another substrate-bound GST monomer and catalyzes a disulphide bridge between the two glutathione molecules

Ultimately, there is an increase in hepatocyte proliferation, which was reversed by the administration of the ROS scavenger L-glutathione

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