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Briefly, we dissolved the powder OA (O-1008 Sigma-Aldrich, Germany) at a final concentration of 12 mM in phosphate-buffered saline (PBS

These stiff gels activate the mechanosensitive ion channel (MIC) TRPV4, which upregulates the activity of the phatidylinositol 3-kinase(PI3k)/Akt pathway, triggering the expression of heat shock protein-(HSP-) 70, which protects against stress-induced cell death [119]

Its rationale lies in modulating immune mechanisms implicated in endometriosis pathophysiology, such as inhibition of TNF- and reduction of inflammatory activation in immune cells

L., Brown, M

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