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31 In a trial evaluating semaglutide for weight loss, the incidence of acute pancreatitis was still low (3 of 1,306 participants) despite a higher dose and more significant weight loss, but none of the 655 individuals in the placebo group developed pancreatitis

, The current literature suggests that activation of these receptor complexes influences pathways involved in food intake regulation, gastric physiology, and energy balance

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