The best option depends on your symptoms, lab results, and overall health
For example, in exploratory trials for Alzheimers disease, a specialized oral formulation of MB (methylthioninium chloride, brand name LMTM) was studied at doses as low as 4 mg twice daily (8 mg total per day) and showed some promise in slowing cognitive decline
10.1042/BST20150014 [DOI] [PMC free article] [PubMed] [Google Scholar] Wible RS, Ramanathan C, Sutter CH et al (2018) NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in mus musculus
Nat Struct Mol Biol 26(12):11511157 Li F, Li W, Farzan M, Harrison SC (2005) Structure of SARS coronavirus spike receptor-binding domain complexed with receptor
Since it is hard to heal the skin after a tophus is removed, a skin graft may be needed in some cases