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GHRH injections in elderly men improved some measures of muscle strength (upright row, shoulder press) but did not consistently improve physical function or IGF-I levels

10.1016/j.pharmthera.2025.108861 9 AslamH.AlbaqamiF.RehmanN

Nagashima M, Watanabe T, Terasaki M, Tomoyasu M, Nohtomi K, Kim-Kaneyama J, Miyazaki A, Hirano T

As Drucker points out, 'The strange thing is that you can't find many GLP-1 receptors in all these other organs where GLP-1 seems to work' (Lunenfeld-Tanenbaum Research Institute)

If additional glycaemic control is needed after at least 4 weeks, the dose may be increased to 1 mg once weekly and potentially to 2 mg once weekly if required and tolerated