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Set a consistent injection day

Three experimental groups were established: group A (non-targeted ORI@Lipo), group B (targeted ORI@CPD-Lipo), and group C (ORI@CPD-Lipo plus CKAAKN peptide as a blocking group)

4 Immunohistochemistry of interleukin-6 (IL-6) in the dorsal root ganglion (DRG) and spinal cord (SC) at phases (A) 1 and (B) 2 Graph (bottom) represents the number of immunostained cells in the DRG and SC (mean SD)

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While the effects of PGRMC1 on cholesterol synthesis mediated by CYP51 have been well documented in yeast 19,41 and human cells 34 , it has not been clear whether drug-metabolizing CYP activities are regulated by PGRMC1