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There have been reports of a number of changes in the concentrations of several neuropeptides in PD brain, which are mainly significant decreases in (Jimnez-Jimnez, 1994): (a) met-enkephalin (MET-ENK), substantia P (SP), and cholecystokinine 8 (CCK-8) in the substantia nigra

Also, some people take B12 as their bodies cannot produce it

J Neurosurg Anesthesiol 36(4): 278282

Acetyl-L-carnitine (ALCAR) is an ester of L-carnitine and plays a major role in normal mitochondrial function, being a transport molecule for free fatty acids and an important acetyl-group donor in high-energy metabolism and free fatty acid beta-oxidation [9,10]

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