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A study in 2019 in the Journal of Human Reproductive Sciences found that oxidative stress is associated with decreased sperm motility, increased sperm DNA damage, and an increased risk of miscarriage and genetic abnormalities

Non-alcoholic fatty liver disease and risk of incident diabetes mellitus: an updated meta-analysis of 501 022 adult individuals

Prenatal and perinatal analgesic exposure and autism: an ecological link.

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(2)Add the obtained ammonium salt of orotate into 2700mL of aqueous ethanol solution, where the mass percentage of ethanol is 10%, warm up to 80 to dissolve the orotate, and then add 241.8g of levulinic acid, keep the reaction at this temperature for 3 hours, cool down to 0 , the product was precipitated, filtered to obtain levulinic acid orotate 296g