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Three landmark publications establish the current scientific foundation: The Jastreboff et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Matic M, Bryzgalova G, Gao H, Antonson P, Humire P, Omoto Y, Portwood N, Pramfalk C, Efendic S, Berggren PO, Gustafsson J, Dahlman-Wright K

That approach bypasses the pituitary entirely