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P66Shc normally resides in the cytosol where it is involved in signaling from tyrosine kinases to Ras

10.1074/jbc.R113.544635 J

In addition, expression levels of ferroptosis, including Gpx4 , Nrf2 , Acsl4 , Alox15 , and Slc7a11 , were disrupted in SD (Fig

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