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This is common in the first 48 weeks

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Moreover, dapagliflozin suppresses the high-glucose-induced gene expression of inflammatory cytokines and oxidative stress in cultured proximal tubular epithelial (mProx24) cells [87]

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Only 7% report discontinuing within one month or less of starting, and nearly all (97%) report discontinuation within the first year

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Glycemic Efficacy, Weight Effects, and Safety of Once-Weekly Glucagon-Like Peptide-1 Receptor Agonists

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