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The function of NRF2 is ubiquitously conserved across different cell types, but it is widely expressed in the central nervous system (CNS), where it regulates a range of functions including redox balance, xenobiotic metabolism, inflammation, and proteostasis (Cuadrado 2022)

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2) In addition to testing various doses of cagrilintide, the peptide was also tested in combination with semaglutide, a GLP-1 receptor agonist, in order to assess the impact treatment has on HbA1c levels in participants diagnosed with type 2 diabetes mellitus

From this data we conclude that MBTH-based kinetic experiments are a good alternative to the kinetic determinations described so far