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Flow cytometry results showed that, compared with control CD8 + T cells, ID8-luc-p53 / significantly induced CD8 + T cell senescence, OA further exacerbated the CD8 + T cell senescence induced by ID8-luc-p53 / cells (Fig

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In addition, pharmacological and genetic suppression of this pathway prevented the differentiation of myeloid descendant cells into MDSCs, leading to significant tumor regression in mice [67]

HO-1:Heme Oxygenase-1

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