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Semaglutide, a GLP-1 receptor agonist marketed as Ozempic, Wegovy, and Rybelsus, is FDA-approved for type 2 diabetes and chronic weight management

The once-weekly dosing and its extended duration of action allow for more stable blood glucose levels over time, and for individuals using it for weight loss, that extended half-life also continuously suppresses appetite

For GLP-1 users, the magnitude of lean body mass loss can be on par with the loss experienced after bariatric surgery, cancer treatment, or 10 years of ageing

What monitoring protocol do you use for patients on this therapy

IDO1 expression in melanoma metastases is low and associated with improved overall survival