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Publication Bias The assessment of publication bias across the five analyzed outcomes - semaglutide, exenatide, liraglutide, orlistat, and post-discontinuation at 12 weeks - utilized multiple statistical methods, including Beggs rank correlation test, Eggers test of the intercept, Fail-safe N, and Duval and Tweedies Trim and Fill method, as provided in the Appendix (Supplementary Figures 8-12)