5-Amino-1MQ is a small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme overexpressed in obese fat tissue that depletes NAD+ precursors and SAM
While it has been in research for over 20 years, it has recently gained a second life thanks to the massive public interest in peptide therapy and the rise of GLP-1 medications.
10.1016/s0928-4257(99)00123-0 [DOI] [PubMed] [Google Scholar] Skorjanec S., Dolovski Z., Kocman I., Brcic L., Blagaic Boban A., Batelja L., et al
[41] : 973974 Exclusive or near-exclusive breastfeeding beyond six months is a strong indicator of low serum vitamin status in nursing infants
For those willing to accept this level of uncertainty, the risk-benefit calculation may still favor trying BPC-157, especially given its favorable safety profile and the limited options for chronic back pain sufferers